Main spellings (~95%)
The /ju/ sound combines a quick /j/ glide with the /u/ vowel. Four spellings cover almost all words.
⟨u⟩ ~35%
The letter ⟨u⟩ says /ju/ in open syllables and before certain consonants.
⟨u_e⟩ ~40%
The split digraph ⟨u_e⟩ (u-consonant-e) is the most common spelling in one-syllable words.
⟨ue⟩ ~15%
Common at the end of words.
⟨ew⟩ ~5%
After certain consonants (t, d, n, l, s, th), the /j/ disappears — this is called yod-dropping. Compare: music (with /j/) vs tune (often without /j/ in American English).